David S. Geldmacher, MD, FACP
Charles and Patsy Collat Professor of Neurology
Director, Division of Memory Disorders and Behavioral Neurology
University of Alabama – Birmingham
Carlos Rojas-Fernandez, BSc(Pharm), PharmD
Schlegel Research Chair in Geriatric Pharmacotherapy
Schlegel-UW Research Institute on Aging
& School of Pharmacy
University of Waterloo
Elizabeth M. Galik, PhD, CRNP
University of Maryland School of Nursing
Mary Campagnolo, MD, MBA, FAAFP, DABFM, CAQ-Geriatrics
Virtua-Family Medicine of Mansfield
Family Physicians: 0.5 Prescribed credit
Nurses: 0.5 Contact Hours
Pharmacists: 0.5 Contact Hour (0.05 CEU) Medium
The burden of Alzheimer’s disease (AD) is well known; in the United States, $148 billion is spent on the care of more than 5 million individuals with AD—a number that is expected to climb to 7.7 million by the year 2030. It is now the sixth leading cause of death in Americans older than 65 years. While current therapies cannot halt the disease, active medical management can significantly improve the quality of life for patients with AD and their caregivers. This newsletter will consider the importance of decreasing and eliminating unnecessary medications, and examine the role of specific pharmacologic agents, particularly with regard to appropriate dosing and duration of treatment, potential drug-drug interactions, and adverse effect profiles.
. Target Audience
Senior care clinicians including family physicians and other primary care physicians, long-term care (LTC) physicians and nurses, consultant pharmacists, and others interested in the care of older patients with Alzheimer’s disease.
Upon completion of this educational activity, the participant should be able to:
Describe how to avoid unnecessary polypharmacy when managing patients with moderate-to-severe AD.
Develop individualized AD care plans to maximize clinical efficacy and safety in patients with moderate-to-severe AD.
It is the policy of the AAFP, ASCP, and NADONA to ensure balance, independence, objectivity and scientific rigor in all of its educational activities including those which are sponsored and cosponsored. All faculty are expected to disclose any significant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services discussed in an educational presentation. The intent of this disclosure is not to prevent a presenter with significant financial interest or other relationship from making the presentation, but rather to provide the audience with information with which they can make their own judgments. It remains for the audience to determine whether the speaker's interests or relationships may influence the presentation with regard to exposition or conclusion. Faculty are also expected to openly disclose any off-label, experimental, or investigational use of drugs or devices in their presentations.
Dr. Geldmacher discloses the following: Consultant: Bayer, Eisai, Glaxo, Janssen; Grant/Research Support: Baxter, BMS, Janssen, Novartis, Pfizer.
Dr. Rojas-Fernandez has no relevant financial conflicts to disclose.
Dr. Galik discloses the following: Consultant: Novartis.
Dr. Campangolo has no relevant financial conflicts to disclose.
Ms. Dechevalier has no relevant financial conflicts to disclose.
Dr. Gerber has no relevant financial conflicts to disclose.
Ms. Barrett has no relevant financial conflicts to disclose.
Ms. Dornberger has no relevant financial conflicts to disclose.
Ms. Hines has no relevant financial conflicts to disclose.
This educational activity may contain discussion of published and/or investigational uses of pharmaceutical agents. Some uses of these agents may not have been approved by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Credit Statements
This Enduring Material activity, Clinical Insights in Geriatrics:
Preventing Adverse Events in Pharmacologic Therapy for Moderate-to-Severe
Alzheimer’s Disease, has been reviewed and is acceptable for up to 0.50 Prescribed credits by the American Academy of Family Physicians. AAFP accreditation begins December 5, 2012. Term of approval is for one year from this date. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The American Society of Consultant Pharmacists (ASCP) is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This knowledge-based activity, ACPE Universal Activity #0203-9999-12-156-H01-P, has been assigned 0.5 Contact Hour (0.05 CEU).
NADONA/LTC is an approved provider of continuing nursing education by Georgia Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation #1088. This activity provides 0.5 contact hour by NADONA/LTC.
Participants must view the activity in its entirety, successfully complete the post-test, and submit an evaluation to receive continuing pharmacy education credit. Credit will be awarded for a score of 80% or better, and a statement may be printed immediately after passing the post-test.
There is no fee to participate in this educational activity. Commercial Support Statements
This activity is supported by an educational grant from Forest Laboratories, Inc.
Minimum System Requirements:
• Pentium III, 600 MHz or Equivalent Processor
• 512 MB of RAM
• Windows XP, Vista, or 7
• Mac OS X
• 800x600 Monitor Resolution
• 16-bit Color
• 16 bit Sound Card with Speakers
The next screen will permit you to check for or download the Flash player required to run this program and to begin the program presentation. The activity will take approximately 30 minutes to complete.
After the activity has finished, click on the "Post-test" button.
Instructions for completing and submitting the post-test and evaluation are provided on the post-test screen.
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© 2012, Medical Communications Media, Inc. All rights reserved. None of the contents may be reproduced in any form without prior written permission from the publisher. The opinions expressed in this educational activity are those of the faculty and do not necessarily reflect the opinions or recommendations of their affiliated institutions, the publisher, ASCP, NJAFP, NADONA, or Forest Laboratories, Inc. Any medications, diagnostic procedures, or treatments discussed by the faculty should not be used by clinicians or other health care professionals without first evaluating their patients’ conditions, considering possible contraindications or risks, reviewing any applicable manufacturer’s product information, and comparing any therapeutic approach with the recommendations of other authorities.